In these studies, the potential for the influence of sleep disturbance on the true pattern of BP or IOP variation, which can affect a patient's MOPP fluctuation profile, has not been significantly considered. However, in those studies, patients were awakened during sleep in the middle of the night (e.g., 3 AM) to obtain BP and IOP measurements, which disturbed their physiologic sleep patterns. noted that marked circadian mean ocular perfusion pressure (MOPP) fluctuation is associated with nocturnal BP reduction, and circadian MOPP fluctuation was the most consistent clinical risk factor for glaucoma severity in normal tension glaucoma (NTG) patients. Many studies have investigated circadian OPP fluctuation as a risk factor for glaucoma. Just as both blood pressure (BP) and IOP follow a circadian rhythm, OPP, which is derived from BP and IOP, also has circadian variation. Several large, population-based studies have demonstrated that decreased OPP is related to increased prevalence of glaucoma. Ocular perfusion pressure (OPP) is calculated as two-thirds of mean arterial pressure (MAP) minus IOP. However, numerous studies have suggested that vascular factors also contribute to the development of glaucomatous optic neuropathy. Intraocular pressure (IOP) is a well-known significant risk factor in the development and progression of glaucoma, and clinical management of glaucoma patients mainly focuses on controlling glaucoma.
0 kommentar(er)
